Anion binding by biotin[6]uril in water

Research output: Contribution to journalLetterResearchpeer-review


In this contribution we show that the newly discovered 6 + 6 biotin-formaldehyde macrocycle Biotin[6]uril binds a variety of anionic guest molecules in water. We discuss how and why the anions are bound based on data obtained using NMR spectroscopy, mass spectrometry, isothermal titration calorimetry (ITC), computational calculations and single crystal X-ray crystallography.
Original languageEnglish
JournalOrganic & Biomolecular Chemistry
Issue number2
Pages (from-to)369-373
Number of pages5
Publication statusPublished - 2015

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